January 27, 2006
The Barriers to Entry for Medical Research

By Froma Harrop

WEST PALM BEACH, Fla. -- "Goofy" is how scientists describe the jig they must dance to do federally funded medical research in the age of Bush. For instance, The Burnham Institute in La Jolla, Calif., maintains separate labs for work with embryonic stem cells, which President Bush has virtually put off limits to government funding. It slaps special stickers on equipment bought with National Institutes of Health grants, lest the machines be used on unauthorized cell lines.

Florida wants to create a medical research hub here in Palm Beach County. Biotech delivers good jobs, and Gov. Jeb Bush is courting Burnham with hefty subsidies. The stars seem in place for Burnham to build in the Sunshine State, except for one thing: The governor thinks embryonic stem cell research is evil.

Burnham is already dealing with the craziness from Washington. Does it want another layer of aggravation on the state level, as well?

Most Americans regard embryonic stem cell research as a potential gift to humankind. The cutting-edge science may someday produce cures for Alzheimer's, diabetes and other degenerative diseases. But it requires the destruction of embryos. Some "pro-life" activists consider these tiny clusters of cells, created in lab dishes, as human beings. Jeb Bush has condemned embryonic stem cell research as the act of "taking a life to save a life."

The thinking in Florida is that a local Burnham lab would steer clear of research involving embryos. Scripps Research Institute, also based in La Jolla, is already here and doing work with adult stem cells, which is not controversial. For the record, Scripps says it never agreed to any ban on embryonic stem cell research -- and would not have taken Florida's offer (including a $310 million incentive package) under such conditions.

But Scripps has never been much of a player in embryonic stem cell research. Burnham is in its big leagues. CEO John Reed sits on the board overseeing the $3 billion that voters in California approved to support the research.

True, Gov. Bush does have a history of modifying his "pro-life" stances when money is involved. Florida's many fertility clinics routinely throw out unused embryos, but Bush has never suggested closing them down. And his preference for low taxes has always trumped any moral qualms over Florida's high percentage of medically uninsured residents -- some of whom die for lack of health care. With stem cell products projected to become a $10 billion industry by 2015, Bush may forget his objection to much of the most promising research in the field.

Still, it's hard to fathom why any self-respecting research institute would do business in a state whose leadership portrays its proudest work as morally reprehensible. Sure, Florida might tolerate it. But does Burnham really want to deal with a governor who asserts that its researchers back in California are "taking lives" in their labs?

Other states, meanwhile, are supporting the science with full hearts, as well as money. California, Massachusetts and New Jersey have gone as far as approving therapeutic cloning, which is a preferred (though controversial) means of creating embryonic stem cells.

Governors in more socially conservative states are openly defending embryonic stem cell research. In Missouri, Gov. Matt Blunt, an anti-abortion Republican, vetoed legislation that would have made this work a felony. The Stowers Institute for Medical Research in Kansas City, Mo., wants to build another facility there, but it won't put a shovel in the ground until all threats against embryonic stem cell research are removed.

Floridians seem split on the issue. A bill in the state legislature would let public money be spent on embryonic stem cell research -- with lots of restrictions attached. There nevertheless remains powerful opposition to the work. And Gov. Bush has never backed down from all but calling it murder.

Bio researchers have to ask themselves: Isn't life already complicated enough with brother George playing games over the stem cell issue in Washington? It takes a certain masochism to voluntarily go where scientists might have to slap state stickers alongside the federal ones on research equipment.

An institute dedicated to the promise of embryonic stem cell research dare not ignore reality. In Jeb Bush's Florida, Goofy can be more than a character at Disney World.

Copyright 2006 Creators Syndicate

Froma Harrop

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